研究内容

• CABEVに対するルキソリチニブの効果を検証する医師主導治験の結果の論文：JAK1/2 inhibitor ruxolitinib for the treatment of systemic chronic active Epstein-Barr virus disease: a phase 2 study
• 新規の感染細胞同定法（EBER flow FISH法）の開発成果の論文：Highly sensitive detection of Epstein-Barr virus-infected cells by EBER flow FISH
• HVLPDの重症化マーカーの検討：Monokine induced by gamma interferon as a marker of systemic hydroa vaccniforme lymphoproliferative disorder
• CAEBVも含むEBV-HLHの患者末梢血のンシングルセル解析の論文：Single-Cell Transcriptomic Analysis of Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis
• CAEBVのガイドラインに関する総説：Updated guidelines for chronic active Epstein-Barr virus disease
• HVLPDの重症化マーカーの検討：Coexpression of natural killer cell antigens by T-cell large granular lymphocytes in hydroa vacciniforme lymphoproliferative disorder and the involvement of Vδ1 + epithelial-type γδT cells
• HVLPDとSMBAの診断に関する論文：Diagnostic and disease severity determination criteria for hydroa vacciniforme lymphoproliferative disorders and severe mosquito bite allergy
• 単施設での成人CAEBV患者を含む臍帯血移植成績の論文：Unrelated cord blood transplantation for adult-onset EBV-associated T-cell and NK-cell lymphoproliferative disorders
• CAEBV患者の血中インターフェロンγの意義についての論文：Plasma interferon-γ concentration: a potential biomarker of disease activity of systemic chronic active Epstein-Barr virus infection.
• 日本の移植レジストリTRUMPデータを用いたCAEBVに対する移植成績の論文：Registry data analysis of hematopoietic stem cell transplantation on systemic chronic active Epstein-Barr virus infection patients in Japan
• 日本の全国調査で明らかになったCAEBVの臨床像、治療実態の論文：Nationwide survey of systemic chronic active EBV infection in Japan in accordance with the new WHO classification
• 単施設での小児CAEBV患者移植成績の論文：A case series of CAEBV of children and young adults treated with reduced intensity conditioning and allogeneic bone marrow transplantation; a single center study